Abstract | OBJECTIVE: METHODS: 64 male smokers with moderate to advanced periodontitis were randomly divided into two groups: SRP alone (SRP) and SRP plus minocycline (SRP+M). All clinical parameters including plaque index (Pll), gingival index (GI), bleeding on probing (BOP), probing depth (PD) and attachment gain were recorded at baseline, 3 and 6 months after treatment. RESULTS: According to PlI, GI and BOP, there was no significant difference between the two groups at 3 and 6 months after periodontal therapy (1 > 0.05). However, PD reduction and attachment gain were significantly greater for SRP+M than that for SRP (P < 0.05). For SRP+M and SRP groups, PD reduction were 1.98 mm and 1.32 mm, and attachment gain were 1.87 mm and 1.14 mm respectively. Deep pockets in SRP+M group showed more obvious PD reduction (3.48 mm versus 2.21 mm, P < 0.01) and attachment gain (2.62 mm versus 1.23 zmm, P < 0.01) than that in SRP group. CONCLUSION:
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Authors | Ning Zhao, Shao-Hua Ge, Guang-Yao Ding |
Journal | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
(Hua Xi Kou Qiang Yi Xue Za Zhi)
Vol. 24
Issue 1
Pg. 32-5
(Feb 2006)
ISSN: 1000-1182 [Print] China |
PMID | 16541651
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Minocycline
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Topics |
- Adult
- Anti-Bacterial Agents
- Chronic Periodontitis
- Dental Plaque Index
- Dental Scaling
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Minocycline
- Periodontal Attachment Loss
- Periodontal Index
- Periodontal Pocket
- Periodontitis
- Root Planing
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