Abstract | BACKGROUND:
Oil Red O, a stain commonly used to demonstrate lipid in frozen tissue, also may be used to stain air-dried cytologic specimens. OBJECTIVE: The purpose of this study was to prospectively evaluate the value of Oil Red O in identifying lipid to aid in the differentiation of liposarcomas from other types of sarcoma. METHODS: Twelve tumor specimens from dogs were evaluated. The tumors were included in the study if initial cytologic evaluation indicated a sarcoma, and if histologic confirmation was available. Oil Red O was applied to all cytologic specimens. RESULTS: CONCLUSION: Our results suggest that Oil Red O staining may be an easy, inexpensive, and useful diagnostic tool for the differentiation of liposarcoma from other mesenchymal neoplasms.
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Authors | Carlo Masserdotti, Ugo Bonfanti, Davide De Lorenzi, Nicola Ottolini |
Journal | Veterinary clinical pathology
(Vet Clin Pathol)
Vol. 35
Issue 1
Pg. 37-41
(Mar 2006)
ISSN: 0275-6382 [Print] United States |
PMID | 16511789
(Publication Type: Journal Article)
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Chemical References |
- Azo Compounds
- Coloring Agents
- oil red O
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Topics |
- Animals
- Azo Compounds
(analysis)
- Coloring Agents
(analysis)
- Dog Diseases
(diagnosis)
- Dogs
- Liposarcoma
(diagnosis, veterinary)
- Staining and Labeling
(methods)
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