Abstract | BACKGROUND: METHODS: RESULTS: There were 147 patients in each group and the groups were evenly matched for putative risk factors at baseline. Patients in the enema group had more anastomotic leaks requiring reoperation than those in the PEG group (4.1 versus 0 per cent, P = 0.013; relative risk 2.04 (95 per cent confidence interval (c.i.) 1.82 to 2.30)). The mortality rate was higher in the PEG group (2.7 versus 0.7 per cent, P = 0.176; odds ratio 1.62 (95 per cent c.i. 0.45 to 36.98)). CONCLUSION: Bowel preparation with a phosphate enema was associated with an increased risk of anastomotic leakage requiring reoperation compared with oral PEG. These results do not support the routine use of a phosphate enema in patients undergoing elective colorectal surgery.
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Authors | C Platell, N Barwood, G Makin |
Journal | The British journal of surgery
(Br J Surg)
Vol. 93
Issue 4
Pg. 427-33
(Apr 2006)
ISSN: 0007-1323 [Print] England |
PMID | 16491463
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Cathartics
- Drug Combinations
- Phosphates
- Sulfates
- glycoprep
- Polyethylene Glycols
- Sodium Chloride
- Potassium Chloride
- Sodium Bicarbonate
- sodium phosphate
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Topics |
- Administration, Oral
- Adult
- Aged
- Aged, 80 and over
- Cathartics
(therapeutic use)
- Colon
(surgery)
- Drug Combinations
- Elective Surgical Procedures
(methods)
- Enema
(methods)
- Female
- Humans
- Male
- Middle Aged
- Phosphates
(therapeutic use)
- Polyethylene Glycols
(therapeutic use)
- Potassium Chloride
(therapeutic use)
- Preoperative Care
(methods)
- Rectum
(surgery)
- Sodium Bicarbonate
(therapeutic use)
- Sodium Chloride
(therapeutic use)
- Sulfates
(therapeutic use)
- Surgical Wound Dehiscence
(prevention & control)
- Surgical Wound Infection
(prevention & control)
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