Abstract |
Focal dermal hypoplasia ( Goltz) syndrome is a rare genetic disorder characterized by cutaneous, ectodermal and mesodermal defects. We present a case in which painful, exophytic granulation tissue has been the main symptom over the past 15 years. After unsatisfactory results with a number of treatment modalities including topical steroids, silver-nitrate applications, cryotherapy, curettage, excision and pulsed-dye laser, we achieved significant benefit with curettage in combination with photodynamic therapy. Although impaired wound healing has been described in focal dermal hypoplasia, this is, to our knowledge, the first time that pyogenic granuloma-like lesions have been reported.
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Authors | R Mallipeddi, S I Chaudhry, C R Darley, H A Kurwa |
Journal | Clinical and experimental dermatology
(Clin Exp Dermatol)
Vol. 31
Issue 2
Pg. 228-31
(Mar 2006)
ISSN: 0307-6938 [Print] England |
PMID | 16487098
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Photosensitizing Agents
- methyl 5-aminolevulinate
- Aminolevulinic Acid
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Topics |
- Adult
- Aminolevulinic Acid
(analogs & derivatives, therapeutic use)
- Curettage
- Female
- Focal Dermal Hypoplasia
(drug therapy, pathology, surgery)
- Granulation Tissue
(pathology)
- Humans
- Photochemotherapy
(methods)
- Photosensitizing Agents
(therapeutic use)
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