[Anesthesia in patients with glucose-6-phosphate dehydrogenase deficiency: case report and perioperative anesthesiologic management].

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a frequent congenital human enzyme defect, is the most frequent cause of hemolytic anemia triggered by drugs or infectious diseases. Drugs which induce acute hemolysis in patients with G6PD deficiency are often used in anesthesia and perioperative pain therapy. Considering the fact that patients from geographic regions with a high prevalence of the disease are often treated in European hospitals, special attention should be paid to this problem. We report a case of a 30-year-old female patient with favism and review the disease and anesthesia-related implications.

• Authors: A L Depta, G Erdös, C Werner
• Journal: Der Anaesthesist (Anaesthesist) Vol. 55 Issue 5 Pg. 550-4 (May 2006) ISSN: 1432-055X [Electronic] Germany
• Vernacular Title: Anästhesie bei Patienten mit Glukose-6-Phosphat-Dehydrogenase-Mangel: Fallbericht und perioperatives anästhesiologisches Management.
• PMID: 16485110 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anesthetics
• Glutathione

Topics

• Adult
• Anesthesia
• Anesthetics (adverse effects)
• Diagnosis, Differential
• Favism (blood, complications, genetics)
• Female
• Glucosephosphate Dehydrogenase Deficiency (blood, complications, genetics)
• Glutathione (metabolism)
• Hemolysis (drug effects)
• Humans
• Preanesthetic Medication
• Thyroidectomy