[Experience with using etaperazine (perphenazine) in the treatment of patients with schizophrenia in a preschool psychiatric department].

Abstract

The results of the treatment with perphenazine of 58 patients aged 5 to 7 years suffering from different forms of schizophrenia have been analyzed. Perphenazine was used in doses of 6 to 45 mg a day. The dosage was progressively increased until the optimal clinical effect was attained. The relationship was discovered between the range of psychopharmacological activity (from stimulating, organizing to antipsychotic and sedative) and the drug doses. The efficacy of the treatment with perphenazine correlated with the forms of schizophrenia, predominant syndromes in the disease clinical picture, and different stages of the process by the treatment commencement. Low toxicity and good tolerance of perphenazine, no pronounced side effects and complications were recorded. This made it possible to administer a wide range of the drug doses in the patients of the age group under study.

• Authors: M E Proselkova, N V Uzhanov
• Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 91 Issue 1 Pg. 120-2 ( 1991) ISSN: 0044-4588 [Print] Russia (Federation)
• Vernacular Title: Opyt primeneniia etaperazina (perfenazina) pri lechenii bol'nykh shizofrenieĭ v doshkol'nom psikhiatricheskom otdelenii.
• PMID: 1647092 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Perphenazine

Topics

• Child
• Child Health Services (organization & administration)
• Child, Preschool
• Dose-Response Relationship, Drug
• Hospitals, Pediatric (organization & administration)
• Humans
• Mental Health Services (organization & administration)
• Moscow
• Perphenazine (administration & dosage)
• Psychiatric Department, Hospital (organization & administration)
• Schizophrenia, Childhood (drug therapy)