| Abstract | Botulinum toxin has been shown to effectively treat several types of neurological disorders. It has recently been evaluated for the treatment of tension-type headaches in patients who are unable to tolerate or cannot benefit from standard therapies. Most of the open design studies seem to present positive results. However, the randomized, double-blind, placebo-controlled studies present contradictory results for the efficacy of botulinum toxin. Based on these data, further controlled trials of botulinum toxin are needed to evaluate its effects on tension headaches and to determine optimal injection sites, doses, and frequency of treatments. |
| Authors | Dima Rozen, Joyti Sharma
(Affiliation: Department of Anesthesiology and Pain Management, Box 1010, Mount Sinai Medical Center, One East 100th Street, New York, NY 10029-6574, USA. dimarozen at hotmail.com)
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| Journal | The Mount Sinai journal of medicine, New York
(Mt Sinai J Med)
Vol. 73
Issue 1
Pg. 493-8
(Jan 2006)
ISSN: 0027-2507 United States |
| PMID | 16470328
(Publication Type: Journal Article, Review)
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| Chemical References |
- Botulinum Toxin Type A
- Neuromuscular Agents
|
| Topics |
- Botulinum Toxin Type A
(administration & dosage, therapeutic use)
- Chronic Disease
- Humans
- Injections
- Neuromuscular Agents
(administration & dosage, therapeutic use)
- Tension-Type Headache
(drug therapy, physiopathology)
- Treatment Outcome
|
