In vitro study of DP-bioglass paste for treatment of dentin hypersensitivity.

Abstract

Sealing of exposed dentinal tubules is generally considered the most effective strategy to treat dentin hypersensitivity. On this account, we fabricated a DP-bioglass paste that created a homogeneous blockage on open dentinal tubules and formed a deep precipitate within dentinal tubules. DP-bioglass paste was prepared by mixing 20% to 60% phosphoric acid and DP-bioglass to treat dentin surfaces. CO2 laser irradiation was used to melt the DP-bioglass paste. The results demonstrated that 30% phosphoric acid was the optimum concentration to produce homogeneous occlusion on exposed dentinal tubules and 60 microm of sealing depth. CO2 laser irradiation could melt the DP-bioglass paste and create about 10 microm of sealing depth. Moreover, temperature rise during CO2 laser irradiation was only 4.86 +/- 0.47 degrees C. The results presented in this work suggested that DP-bioglass paste could produce considerable sealing depth in dentinal tubules with the potential of prolonging the therapeutic effect efficaciously.

• Authors: Bor-Shiunn Lee, Hsin-Yi Tsai, Yi-Ling Tsai, Wan-Hong Lan, Chun-Pin Lin
• Journal: Dental materials journal (Dent Mater J) Vol. 24 Issue 4 Pg. 562-9 (Dec 2005) ISSN: 0287-4547 [Print] Japan
• PMID: 16445019 (Publication Type: Journal Article)

Chemical References

• DP-bioactive glass paste
• Dental Cements
• Phosphoric Acids
• phosphoric acid

Topics

• Adolescent
• Adult
• Crystallography, X-Ray
• Dental Cements (chemistry, pharmacology, therapeutic use)
• Dentin (ultrastructure)
• Dentin Permeability (drug effects)
• Dentin Sensitivity (drug therapy)
• Hot Temperature
• Humans
• Lasers
• Microscopy, Electron, Scanning
• Molar
• Phosphoric Acids
• Spectrometry, X-Ray Emission