Progesterone receptors in bilateral ovarian ependymoma presenting in pregnancy.

Abstract

We present a case of a 25-year-old patient at term pregnancy who presented with a bilateral ovarian neoplasm that was histologically and immunohistochemically indistinguishable from ependymoma of the central nervous system. Progesterone receptors were detected in primary and recurrent neoplasms by immunohistochemistry. This is the first case of this rare neoplasm to present during pregnancy as well as with bilateral ovarian involvement. Together with a previously reported case of recurrent ovarian ependymoma with estrogen and progesterone receptors, this case suggests that hormonal responsiveness of this rare neoplasm may be pathogenically significant.

• Authors: K A Carr, J A Roberts, T S Frank
• Journal: Human pathology (Hum Pathol) Vol. 23 Issue 8 Pg. 962-5 (Aug 1992) ISSN: 0046-8177 [Print] United States
• PMID: 1644443 (Publication Type: Case Reports, Journal Article)

Chemical References

• Receptors, Progesterone

Topics

• Adult
• Ependymoma (chemistry, complications, ultrastructure)
• Female
• Humans
• Immunohistochemistry
• Ovarian Neoplasms (chemistry, complications, ultrastructure)
• Ovary (chemistry, pathology, ultrastructure)
• Pregnancy
• Pregnancy Complications, Neoplastic (diagnosis, pathology)
• Receptors, Progesterone (analysis)