Multicentric Kaposi's sarcoma in a 5-year-old human immunodeficiency virus-negative renal allograft recipient.

Abstract

We describe the clinical and pathologic features of a case of pediatric multicentric Kaposi's sarcoma (KS) associated with allograft transplantation in a human immunodeficiency virus (HIV)-negative child. A lethal polyadenopathic and visceral KS occurred in a 5-year-old Caribbean boy who had undergone an allogenic renal transplantation for diffuse mesangial sclerosis with end-stage renal failure 4 months previously. The HIV-1 and HIV-2 serologies were negative. Despite its rarity, KS must be considered as a differential diagnosis in posttransplantation polyadenopathic or multisystemic syndromes in children.

• Authors: J C Fournet, M Peuchmaur, P Eckart, M F Gagnadoux, J L Stephan, P Hubert, P Niaudet, N Brousse
• Journal: Human pathology (Hum Pathol) Vol. 23 Issue 8 Pg. 956-60 (Aug 1992) ISSN: 0046-8177 [Print] United States
• PMID: 1644441 (Publication Type: Case Reports, Journal Article)

Chemical References

• HIV Antibodies

Topics

• Autopsy
• Child, Preschool
• HIV Antibodies (analysis)
• HIV Seropositivity
• Humans
• Kidney Transplantation (adverse effects, immunology, pathology)
• Male
• Sarcoma, Kaposi (diagnosis, immunology, pathology)
• Transplantation, Homologous