Magnesium profile in autism.

The aim of the present study was to determine and compare plasma and erythrocyte concentrations of magnesium in 12 autistic children (10 boys, 2 girls), 17 children with other autistic spectrum disorders (14 boys, 3 girls), 5 girls with classic Rett syndrome, and 14 normal children (7 boys, 7 girls) of the same age. No differences in intracellular Mg were found between controls and pathological subjects; however, autistic children and children with other autistic spectrum disorders had significantly lower plasma concentrations of Mg than normal subjects (p=0.013 and p=0.02, respectively). Although our study population was small, we conclude that children with autistic spectrum disorders require special dietary management. If these cases are diagnosed at an early stage, they can be helped through diet.
AuthorsMirella Strambi, Mariangela Longini, Joseph Hayek, Silvia Berni, Francesca Macucci, Elisa Scalacci, Piero Vezzosi
JournalBiological trace element research (Biol Trace Elem Res) Vol. 109 Issue 2 Pg. 97-104 (Feb 2006) ISSN: 0163-4984 [Print] United States
PMID16443999 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Magnesium
  • Adolescent
  • Autistic Disorder (blood, diet therapy)
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Data Interpretation, Statistical
  • Dietary Supplements
  • Erythrocytes (chemistry)
  • Female
  • Humans
  • Infant
  • Magnesium (blood, therapeutic use)
  • Male
  • Rett Syndrome (blood, diet therapy)

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