Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study.

Twenty dogs with atopy or idiopathic pruritus were treated in a double-blinded clinical trial with computer-randomized and computer-generated sequences of 4 fatty acid-containing products: evening primrose oil, cold water marine fish oil, DVM Derm Caps, and EfaVet. Each dog received each product for a 2-week period. Five of 20 dogs (25%) had a good-to-excellent reduction in their level of pruritus with at least 1 of the products: evening primrose oil (2 dogs), DVM Derm Caps (1), EfaVet (1), DVM Derm Caps and cold water marine fish oil (1). Only 1 dog experienced a side effect (loose stools). Clinical response to fatty acid supplements appeared to be quite individualized, and independent of age, breed, sex, weight, duration of disease, specific diagnosis, or number of positive intradermal test reactions.
AuthorsD W Scott, W H Miller Jr, G A Decker, J R Wellington
JournalThe Cornell veterinarian (Cornell Vet) Vol. 82 Issue 3 Pg. 319-29 (Jul 1992) ISSN: 0010-8901 [Print] UNITED STATES
PMID1643883 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Dermatologic Agents
  • Fatty Acids, Essential
  • Fish Oils
  • Linoleic Acids
  • Plant Oils
  • Efamol
  • gamma-Linolenic Acid
  • Animals
  • Dermatologic Agents (therapeutic use)
  • Dog Diseases (drug therapy, etiology)
  • Dogs
  • Fatty Acids, Essential (therapeutic use)
  • Female
  • Fish Oils (therapeutic use)
  • Hypersensitivity (complications, veterinary)
  • Linoleic Acids
  • Male
  • Plant Oils
  • Pruritus (drug therapy, etiology, veterinary)
  • gamma-Linolenic Acid

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