Anecortave acetate.

Abstract

This manuscript reviews the pharmacotherapeutics of the novel, angiostatic cortisene, anecortave acetate suspension, for the treatment of age-related macular degeneration. The chemistry, pharmacokinetics and pharmacodynamics of anecortave acetate are discussed, and the results of the multi-centre, randomised, controlled clinical trials for the treatment of subfoveal choroidal neovascularisation in age-related macular degeneration summarised. It also discusses ongoing clinical trials involving anecortave acetate for dry and wet age-related macular degeneration.

• Authors: Sophie J Bakri, Peter K Kaiser
• Journal: Expert opinion on investigational drugs (Expert Opin Investig Drugs) Vol. 15 Issue 2 Pg. 163-9 (Feb 2006) ISSN: 1744-7658 [Electronic] England
• PMID: 16433595 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Drugs, Investigational
• Pregnadienediols
• anecortave acetate

Topics

• Animals
• Drugs, Investigational (administration & dosage, chemistry)
• Humans
• Macular Degeneration (drug therapy, pathology)
• Pregnadienediols (administration & dosage, chemistry)