Use of trafermin to treat a skin ulcer after repair of a deep auricular laceration: a case report.

Abstract

We used trafermin (recombinant human basic fibroblast growth factor) to treat a skin ulcer (diameter, 1 cm; depth, 2 mm) that developed after an extremely deep auricular laceration was sutured. Excellent results were obtained after use of trafermin for 2 weeks. To our knowledge, we report the first clinical use of trafermin in a patient with a skin ulcer resulting from auricular trauma. Trafermin may promise to be an effective treatment for skin ulcers.

• Authors: Tohru Tanigawa, Meiho Nakayama, Tomohiko Nakamura, Shigeru Inafuku
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 16 Issue 5-6 Pg. 345-6 ( 2005) ISSN: 0954-6634 [Print] England
• PMID: 16428158 (Publication Type: Case Reports, Journal Article)

Chemical References

• Peptide Fragments
• trafermin
• Fibroblast Growth Factors

Topics

• Aged
• Ear, External (injuries)
• Fibroblast Growth Factors (therapeutic use)
• Humans
• Lacerations (surgery)
• Male
• Peptide Fragments (therapeutic use)
• Postoperative Complications
• Skin Ulcer (drug therapy, etiology)