Dramatic improvement of penile venous leakage upon testosterone administration. A case report and review of literature.

Abstract

The main effect of testosterone was long-time assumed to be on sexual interest and, indirectly, on erectile function. Newer insights demonstrate that testosterone deficiency impairs the anatomical, ultrastructural, biological and physiological/functional substrate of penile erection, which can be, at least in part, restored by normalization of plasma testosterone levels. This is a report on a 56-year-old man suffering from diabetes mellitus type II and metabolic syndrome, who had complaints of a severe erectile dysfunction because of venous leakage, confirmed by pharmaco-cavernosography. He was also testosterone deficient (1.8 ng ml(-1)). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage.

• Authors: A A Yassin, F Saad
• Journal: Andrologia (Andrologia) Vol. 38 Issue 1 Pg. 34-7 (Feb 2006) ISSN: 0303-4569 [Print] Germany
• PMID: 16420241 (Publication Type: Case Reports, Journal Article)

Chemical References

• Androgens
• Testosterone

Topics

• Aging (blood, physiology)
• Androgens (therapeutic use)
• Diabetes Mellitus, Type 2 (complications, physiopathology)
• Erectile Dysfunction (drug therapy, etiology, physiopathology)
• Humans
• Impotence, Vasculogenic (blood, complications, diagnosis, drug therapy)
• Male
• Metabolic Syndrome (complications, physiopathology)
• Middle Aged
• Penis (diagnostic imaging, pathology, physiopathology)
• Radiography
• Testosterone (blood, deficiency, physiology, therapeutic use)
• Treatment Outcome