Treatment for simple plantar verrucae: monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone.

Abstract

Verrucae are small, benign, highly vascular epithelial neoplasms that occur singly or in a multiple presentation. Plantar verrucae are usually caused by infection with human papillomavirus types 1, 2, and 4. A clinical trial was conducted to assess the safety and efficacy of monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone in the treatment of simple plantar verrucae. Of 57 patients enrolled in the study, 26 were in the monochloroacetic acid and 10% formaldehyde group and 31 were in the 10% formaldehyde alone group. The overall cure rate for this population was 61.4%. There was no statistically significant difference in the cure rate between treatment groups.

• Authors: Maureen B Jennings, James Ricketti, John Guadara, Wendy Nach, Susan Goodwin
• Journal: Journal of the American Podiatric Medical Association (J Am Podiatr Med Assoc) 2006 Jan-Feb Vol. 96 Issue 1 Pg. 53-8 ISSN: 8750-7315 [Print] United States
• PMID: 16415283 (Publication Type: Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Acetates
• Disinfectants
• Formaldehyde
• chloroacetic acid

Topics

• Acetates (therapeutic use)
• Adult
• Disinfectants (therapeutic use)
• Drug Therapy, Combination
• Female
• Foot Diseases (drug therapy)
• Formaldehyde (therapeutic use)
• Humans
• Male
• Warts (drug therapy)