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Suspected ivermectin toxicosis in a miniature mule foal causing blindness.

Abstract
A 9-week-old miniature mule foal presented to the Veterinary Medical Teaching Hospital for acute blindness, ataxia, and depression following an overdose of an over-the-counter ivermectin-based de-worming medication. Ophthalmic examination and electrodiagnostic evaluation eliminated outer retinal abnormalities as the primary cause of the bilateral blindness, implicating instead a central neurologic effect of the drug. With symptomatic and supportive care, the foal recovered fully and regained its vision.
AuthorsCaryn E Plummer, Maria E Kallberg, Franck J Ollivier, Dennis E Brooks, Kirk N Gelatt
JournalVeterinary ophthalmology (Vet Ophthalmol) 2006 Jan-Feb Vol. 9 Issue 1 Pg. 29-32 ISSN: 1463-5216 [Print] England
PMID16409242 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiparasitic Agents
  • Ivermectin
Topics
  • Animals
  • Animals, Newborn
  • Antiparasitic Agents (poisoning, therapeutic use)
  • Blindness (chemically induced, therapy, veterinary)
  • Drug Overdose (veterinary)
  • Electroretinography (veterinary)
  • Equidae
  • Ivermectin (poisoning, therapeutic use)
  • Male
  • Treatment Outcome

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