[Treatment of a patent duct in neonates].

Abstract

The authors analyze clinical and laboratory aspects of Indomethacin treatment of neonates with a patent ductus arteriosus. From June 1987 to November 1990 the authors treated 19 neonates with a patent ductus arteriosus with Indomethacin. The drug was administered, 0.1-0.3 mg/kg body weight, by the oral route three times/24 or 36 hours. In 17 infants after Indomethacin treatment the duct closed, in two infants the duct did not close during Indomethacin treatment, in three infants the authors observed oliguria which improved after discontinuation of treatment.

• Authors: A Jurko, E Hlaucová, M Fedor, T Klein, A Jurko
• Journal: Ceskoslovenska pediatrie (Cesk Pediatr) Vol. 47 Issue 5 Pg. 265-7 (May 1992) ISSN: 0069-2328 [Print] Czech Republic
• Vernacular Title: Liecba otvoreného duktu v novorodeneckom veku.
• PMID: 1638648 (Publication Type: English Abstract, Journal Article)

Chemical References

• Indomethacin

Topics

• Ductus Arteriosus, Patent (diagnosis, drug therapy)
• Female
• Humans
• Indomethacin (therapeutic use)
• Infant, Newborn
• Male