Abstract | OBJECTIVE: METHODS: Twenty-nine infants admitted to the pediatric intensive care unit of UNICAMP university hospital were studied. Acute viral bronchiolitis was defined according to clinical and radiological criteria. Children with chronic diseases and those that were hemodynamically unstable were excluded. All measurements were taken after 24 to 72 hours' mechanical ventilation, using volumetric capnography and blood gas analysis. Mechanical ventilation time was divided into: < or = 7 days and > 7 days. Association between time on mechanical ventilation and the variables analyzed was determined by Spearman's Correlation Coefficient (r(s)). RESULTS: Time on mechanical ventilation showed a significant positive correlation with PaCO(2) (rs = 0.45, p = 0.01) and ventilation index (rs = 0.51, p = 0.005), and a negative correlation with pH (rs = -0.40, p = 0.03). Ventilation indices of 37, measured between day one and day five, was associated with a progressively increased risk of more than 7 days on mechanical ventilation (OR = 4.2 on the first day to 15.71 on the fourth day). CONCLUSIONS: Ventilation index, PaCO(2) and pH, measured early, were associated with prolonged mechanical ventilation, reflecting the severity of ventilatory disturbance and the need for support.
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Authors | Armando A Almeida-Júnior, Marcos T N da Silva, Celize C B Almeida, Andréa D N Jacomo, Breno M Nery, José D Ribeiro |
Journal | Jornal de pediatria
(J Pediatr (Rio J))
2005 Nov-Dec
Vol. 81
Issue 6
Pg. 466-70
ISSN: 0021-7557 [Print] Brazil |
Vernacular Title | Associação entre índice de ventilação e tempo de ventilação mecânica em lactentes com bronquiolite viral aguda. |
PMID | 16385364
(Publication Type: English Abstract, Journal Article)
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Topics |
- Acute Disease
- Bronchiolitis, Viral
(complications)
- Female
- Humans
- Hydrogen-Ion Concentration
- Infant
- Infant, Newborn
- Male
- Prospective Studies
- Respiration, Artificial
(adverse effects)
- Respiratory Function Tests
- Respiratory Insufficiency
(therapy, virology)
- Risk Factors
- Sensitivity and Specificity
- Time Factors
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