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Sweet's syndrome responding to cyclosporin.

AbstractWe report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed.
AuthorsJ F Bourke, J Berth-Jones, R A Graham-Brown (Affiliation: Department of Dermatology, Leicester Royal Infirmary, U.K.)
JournalThe British journal of dermatology (Br J Dermatol) Vol. 127 Issue 1 Pg. 36-8 (Jul 1992) ISSN: 0007-0963 ENGLAND
PMID1637692 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cyclosporine
Topics
  • Adult
  • Biopsy
  • Cyclosporine (therapeutic use)
  • Female
  • Humans
  • Skin (pathology)
  • Sweet Syndrome (drug therapy, pathology)