| Abstract | We report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed. |
| Authors | J F Bourke, J Berth-Jones, R A Graham-Brown
(Affiliation: Department of Dermatology, Leicester Royal Infirmary, U.K.)
|
| Journal | The British journal of dermatology
(Br J Dermatol)
Vol. 127
Issue 1
Pg. 36-8
(Jul 1992)
ISSN: 0007-0963 ENGLAND |
| PMID | 1637692
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
|
| Topics |
- Adult
- Biopsy
- Cyclosporine
(therapeutic use)
- Female
- Humans
- Skin
(pathology)
- Sweet Syndrome
(drug therapy, pathology)
|