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Daily plasma-exchange for life-threatening class I HELLP syndrome with prevalent pulmonary involvement.

Abstract
HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) is a thrombotic microangiopathy affecting a minority of women with pre-eclampsia and usually resolves after delivery. The role of plasma exchange in HELLP syndrome has to be defined. Herein is reported a case of a primipara with a class I HELLP syndrome with prevalent pulmonary involvement successfully treated with 8 consecutive plasma exchange plus corticosteroids. In class I HELLP syndrome with cardiopulmonary complications early plasma exchange could be considered a therapeutic option.
AuthorsClaudia Del Fante, Cesare Perotti, Gianluca Viarengo, Giuseppe Sala Gallini, Carmine Tinelli, Laura Salvaneschi
JournalTransfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (Transfus Apher Sci) Vol. 34 Issue 1 Pg. 7-9 (Feb 2006) ISSN: 1473-0502 [Print] England
PMID16376616 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Adrenal Cortex Hormones
Topics
  • Adrenal Cortex Hormones (therapeutic use)
  • Adult
  • Female
  • HELLP Syndrome (therapy)
  • Humans
  • Lung (pathology)
  • Plasma
  • Plasma Exchange (methods)
  • Pre-Eclampsia (therapy)
  • Pregnancy
  • Pulmonary Edema (therapy)
  • Time Factors

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