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[Aortic valve replacement for the patient with Osler-Rendu-Weber disease].

Abstract
Osler Rendu-Weber (O-R W) disease (hereditary haemorrhagic telangiectasia) is characterized by an anormality of the peripheral blood vessels which often causes recurrent epistaxis. We presented a case of aortic valve replacement for the patient with O-R-W disease. A 75-year-old woman diagnosed as O-R-W disease with chest pain and dyspnea was admitted. Preoperative transthoratic echocardiography showed severe aortic valve stenosis (AS) with a pressure gradient (from left ventricle to ascending aorta) of 72.5 mmHg. Urgent aortic valve replacement (AVR) was performed after preoperative hormonal (estrogen-progesterone) therapy, that might be effective for bleeding from vascular ectasia. No hemorrhagic tendency was recognized and the postoperative course was uneventful.
AuthorsYoshimasa Seike, H Sato, M Nagashima, T Hori, H Ishitoya, N Hibino, T Tomino, T Nakata
JournalKyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 58 Issue 13 Pg. 1141-4 (Dec 2005) ISSN: 0021-5252 [Print] Japan
PMID16359013 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Aged
  • Aortic Valve (surgery)
  • Aortic Valve Stenosis (surgery)
  • Epistaxis (etiology)
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Telangiectasia, Hereditary Hemorrhagic (complications)

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