[A comparative study of the effects of laser and light-emitting diode irradiation on the wound healing and functional activity of wound exudate leukocytes].

Abstract

The effects of coherent He-Ne laser and non-coherent light-emitting diode radiation on rat skin wound healing and functional activity of wound excudate leukocytes were compared. A comparative pathomorphological analysis showed that the He-Ne laser and light-emitting diode irradiation stimulated the transition of the inflammatory phase of the wound healing into the reparative (proliferative) and scarring phases sequentially. It was also detected that the functional activity of leucocytes changed in a dose-dependent manner. The leukocyte activity was found to be similar in the groups with laser and light-emitting diode irradiation. Thus, we can conclude that coherent laser and non-coherent light-emitting diode radiation have very close effects on wound healing and activity of wound exudate leukocytes, and coherence is not required for this activity.

• Authors: G I Klebanov, N Iu Shuraeva, T V Chichuk, A N Osipov, T G Rudenko, A B Shekhter, Iu A Vladimirov
• Journal: Biofizika (Biofizika) 2005 Nov-Dec Vol. 50 Issue 6 Pg. 1137-44 ISSN: 0006-3029 [Print] Russia (Federation)
• PMID: 16358796 (Publication Type: Comparative Study, English Abstract, Journal Article)

Topics

• Animals
• Cicatrix (metabolism, pathology)
• Dose-Response Relationship, Radiation
• Laser Therapy
• Leukocytes (metabolism, pathology, radiation effects)
• Light
• Low-Level Light Therapy
• Male
• Rats
• Skin (injuries)
• Wound Healing (radiation effects)