Abstract |
The patient was a 78-year-old woman who underwent right hemicolectomy with lymph node dissection (D 2) for cecal cancer in June 2003. Histological diagnosis was moderately differentiated adenocarcinoma, ss, n(-), P 0, H 0, M (-), stage II. Adjuvant chemotherapy was not conducted, and the patient was periodically observed after operation. In April 2004, the serum CEA level was elevated to 14.9 ng/ml. Abdominal CT examinations revealed a tumor, 50 x 35 x 50 mm in size, on the right iliopsoas muscle close to the anastomotic site. Systemic chemotherapy with UFT + Leucovorin was initiated under the diagnosis of local recurrence. Only grade 1 body weight loss,pigmentation, pruritus, and anorexia were recognized during chemotherapy. However, these complications did not require administration. After completion of 6 courses of this chemotherapeutic regimen,the serum CEA level was normalized at 3.1 ng/ml, and CT scan revealed the tumor had disappeared in November 2004. Currently, the patient is free from any signs of recurrence and has maintained a complete remission (CR).
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Authors | Tsunekazu Mizushima, Toshikazu Ito, Hitoshi Mizuno, Yoshihito Souma, Satoshi Kainuma, Hiroaki Yamanaka, Hideto Ozawa, Takashi Kanou, Yasuhiro Nakamori, Kazuhiro Iwase |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 32
Issue 13
Pg. 2129-31
(Dec 2005)
ISSN: 0385-0684 [Print] Japan |
PMID | 16352943
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Drug Combinations
- UFT(R) drug
- Tegafur
- Uracil
- Leucovorin
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Topics |
- Adenocarcinoma
(drug therapy, surgery)
- Aged
- Antineoplastic Combined Chemotherapy Protocols
- Colectomy
- Colonic Neoplasms
(drug therapy, surgery)
- Combined Modality Therapy
- Drug Administration Schedule
- Drug Combinations
- Female
- Humans
- Leucovorin
(administration & dosage)
- Lymph Node Excision
- Neoplasm Recurrence, Local
(drug therapy)
- Remission Induction
- Tegafur
(administration & dosage)
- Uracil
(administration & dosage)
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