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Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in a Crohn's disease patient.

AbstractBACKGROUND:
Several malignancies have been described in association with inflammatory bowel diseases, the most common being adenocarcinoma. Carcinoid tumor and Crohn disease has also been previously reported, however the coexistence of both neoplasms is quite rare and the clinical diagnosis is very difficult. Here we report what we believe to be the fourth case of a mixed adenocarcinoid tumor coexisting with Crohn's disease.
CASE REPORT:
The patient presented with clinical and radiological features of intestinal obstruction. Laparotomy showed a stricturing lesion in the last 6 cm of the terminal ileum with proximal dilation. Only the histology of the resected surgical specimen proved the presence of a mixed adenocarcinoid tumor involving the terminal ileum.
CONCLUSION:
Carcinoid tumor should be suspected in elderly patients with Crohn's disease presenting with intestinal obstruction and laparotomy should be considered to exclude malignancy.
AuthorsUgo Cioffi, Matilde De Simone, Stefano Ferrero, Michele M Ciulla, Alessandro Lemos, Ettore Contessini Avesani
JournalBMC cancer (BMC Cancer) Vol. 5 Pg. 157 (Dec 08 2005) ISSN: 1471-2407 [Electronic] England
PMID16336666 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Chromogranin A
  • Chromogranins
Topics
  • Adenocarcinoma (complications, diagnosis)
  • Carcinoid Tumor (complications, diagnosis)
  • Chromogranin A
  • Chromogranins (metabolism)
  • Crohn Disease (complications, diagnosis)
  • Female
  • Humans
  • Ileal Neoplasms (complications, diagnosis, pathology)
  • Ileum (pathology)
  • Immunohistochemistry
  • Middle Aged
  • Neoplasms, Second Primary (diagnosis)

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