[The effect of muscovite on the quality of gastric ulcer healing].

Abstract

OBJECTIVE:

To explore the effect of muscovite on the quality of gastric ulcer healing.

METHOD:

Gastric ulcers were produced in male rats by serosal application of acetic acid. Rats were gavaged for 14 days with saline, omeprazole and muscovite starting 3 days after ulcer induction. Then the tissue and blood samples were obtained and measured.

RESULT:

In the muscovite group, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, EGF, bFGF were enhanced, and the express of EGFR was stronger.

CONCLUSION:

Muscovite can promote the gastric ulcer healing and improve the quality of gastric ulcer healing.

• Authors: Jian-Min Si, Yun Qian, Jia-Guo Wu
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 30 Issue 19 Pg. 1536-41 (Oct 2005) ISSN: 1001-5302 [Print] China
• PMID: 16335828 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Aluminum Silicates
• Hexosamines
• Materia Medica
• Fibroblast Growth Factor 2
• ErbB Receptors
• Dinoprostone

Topics

• Aluminum Silicates (pharmacology)
• Animals
• Dinoprostone (blood)
• ErbB Receptors (metabolism)
• Fibroblast Growth Factor 2 (metabolism)
• Gastric Mucosa (pathology, physiopathology)
• Hexosamines (metabolism)
• Male
• Materia Medica (pharmacology)
• Mucus (metabolism)
• Rats
• Rats, Wistar
• Stomach Ulcer (chemically induced, pathology, physiopathology)