A case of malignant lymphoma accompanied by Klinefelter's syndrome.

Abstract

A 66-year-old Japanese male with diffuse non-Hodgkin's lymphoma, of the pleomorphic type, complicated with Klinefelter's syndrome is reported. His phisique was characterized by a long arm span, disproportionately longer lower body dimensions and a small sized penis. He had no children. Chromosomal study revealed 47, XXY and hormonal quantification showed hypergonadtropic hypogonadism. Although chemotherapy was administered, his disease took a progressive course and he died. A discussion of chromosomal alteration and oncogenesis and review of the literature are included.

• Authors: M Koyama, K Uejima, T Konishi, M Ishida, M Kato, M Nishigaki, H Mizutani, K Matsumoto, M Kawase, T Tamaki
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 31 Issue 4 Pg. 496-9 (Apr 1992) ISSN: 0918-2918 [Print] Japan
• PMID: 1633357 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Aged
• Humans
• Klinefelter Syndrome (complications, genetics)
• Lymphoma, Non-Hodgkin (complications, genetics, pathology)
• Male