Abstract | PURPOSE: METHODS: RESULTS: A PVD was created in seven out of eight eyes exposed to plasmin or plasmin with gas, however, the macular hole was not closed by either. Closure occurred in two eyes using conventional vitrectomy after the plasmin with gas injection, but peeling the ILM was required in the remaining six eyes. Vitreal fibers and glial cells were not observed on the vitreal surface of the extracted ILM. CONCLUSIONS: A PVD was created safely and reliably although closure of the macular hole did not occur with either plasmin or with plasmin and gas injection. However, vitreous surgery became easier, and it required a shorter time to close the macular hole with intravitreal plasmin.
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Authors | T Sakuma, M Tanaka, M Inoue, A Mizota, M Souri, A Ichinose |
Journal | European journal of ophthalmology
(Eur J Ophthalmol)
2005 Nov-Dec
Vol. 15
Issue 6
Pg. 787-94
ISSN: 1120-6721 [Print] United States |
PMID | 16329067
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Fibrinolytic Agents
- Fibrinolysin
- Sulfur Hexafluoride
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Topics |
- Aged
- Drug Therapy, Combination
- Epiretinal Membrane
(pathology)
- Female
- Fibrinolysin
(administration & dosage)
- Fibrinolytic Agents
(administration & dosage)
- Humans
- Injections
- Male
- Middle Aged
- Retinal Perforations
(diagnosis, drug therapy, surgery)
- Sulfur Hexafluoride
(administration & dosage)
- Tomography, Optical Coherence
- Treatment Outcome
- Visual Acuity
- Vitrectomy
- Vitreous Body
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