HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[A multicenter clinic study of slow-release-gliclazide in type 2 diabetes mellitus].

AbstractOBJECTIVE:
To evaluate the efficacy and safety of 30 mg slow-release-gliclazide (Diamicron MR) on type 2 diabetes patients with the level of blood glucose poorly controlled formerly.
METHODS:
154 type 2 diabetes patients with the level of blood glucose poorly controlled formerly were enrolled and treated with Diamicron MR for 16 weeks. The efficacy of slow-release-gliclazide was evaluated through HbA1c, FPG and 2 h PBG after 16 weeks of treatment period. The safety was evaluated through the adverse events including hypoglycemic episodes and the change of vital signs and clinic laboratory parameters.
RESULTS:
After 16 weeks of treatment period, the HbA1c, FPG and 2 h PBG were decreased by 1.89%, 2.31 mmol/L and 3.94 mmol/L respectively, cutting down 21.6%, 24.5% and 27.8% relatively in comparison with pre-treatment. Glucose metabolism could be significantly improved by taking once-daily Diamicron MR.
CONCLUSION:
Slow-release-gliclazide offers the significant treatment safely, which is important to optimize type 2 diabetes mellitus management.
AuthorsWei-ping Jia, Guang Ning, Xin Gao, Li Yan, Hua-zhang Yang, Ming Li, Jie Hong, Zhi-qiang Lu, Hua Cheng, Yi-qin Qi, Zhong-wen Li, Kun-san Xiang
JournalZhonghua yi xue za zhi (Zhonghua Yi Xue Za Zhi) Vol. 85 Issue 37 Pg. 2636-9 (Sep 28 2005) ISSN: 0376-2491 [Print] China
PMID16321325 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)
Chemical References
  • Hypoglycemic Agents
  • Gliclazide
Topics
  • Adult
  • Diabetes Mellitus, Type 2 (drug therapy)
  • Female
  • Gliclazide (administration & dosage, therapeutic use)
  • Humans
  • Hypoglycemic Agents (administration & dosage, therapeutic use)
  • Male
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: