[Experience of therapy for sepsis in cancer patients with neutropenia].

Abstract

The paper generalizes experience gained in performing 5800 courses of multidrug therapy (MDT) in patients with malignant tumors at various sites, complicated in 68 cases of severe neutropenia (neutrophils less than 500 per microl). Sepsis was diagnosed in 22 cases. With the timely admission of patients with sepsis and neutropenia during complex intensive therapy, their mortality was 22.7%. Emphasis is laid on a role of colony-stimulating factors in the correction of agranulocytosis. Their use decreases the duration of neutropenia, antibiotic therapy, and the length of stay by 1.3 times, as well as the cost of treatment.

• Authors: A E Smirnova, D V Lileev
• Journal: Anesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2005 Sep-Oct Issue 5 Pg. 66-7 ISSN: 0201-7563 [Print] Russia (Federation)
• PMID: 16318058 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Anti-Bacterial Agents (therapeutic use)
• Antineoplastic Combined Chemotherapy Protocols (adverse effects)
• Humans
• Neoplasms (complications, drug therapy)
• Neutropenia (complications, drug therapy)
• Sepsis (drug therapy, etiology)