Anti-inflammatory activity of Croton cuneatus aqueous extract.

Abstract

The aqueous extract of Croton cuneatus Klotz. (Euphorbiaceae), was tested for its antinociceptive effects using chemical and thermal test models in mice. Anti-inflammatory activity was determined in Sprague-Dawley rats in a model of acute plantar inflammation induced by bovine serum albumin. Croton cuneatus aqueous extract at doses of 7 mg/kg showed a significant anti-inflammatory effect compared with commonly used non-stereoidal drugs as ketoprofen, sodium diclofenac and ASA (acetylsalicylic acid).

• Authors: Alírica I Suárez, Zuleyma Blanco, Reinaldo S Compagnone, María M Salazar-Bookaman, Varlin Zapata, Claudia Alvarado
• Journal: Journal of ethnopharmacology (J Ethnopharmacol) Vol. 105 Issue 1-2 Pg. 99-101 (Apr 21 2006) ISSN: 0378-8741 [Print] Ireland
• PMID: 16314057 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents
• Plant Extracts

Topics

• Animals
• Anti-Inflammatory Agents (pharmacology)
• Croton (chemistry)
• Male
• Plant Extracts (pharmacology, toxicity)
• Rats
• Rats, Sprague-Dawley