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Recent advances in antiviral nucleoside and nucleotide therapeutics.

Abstract
Recent developments in nucleoside/nucleotide therapeutics and antiviral drug targets are described covering progress in the development of nucleoside/nucleotide mimetics for the treatment of influenza virus, human immunodeficiency virus type 1, hepatitis B and C virus, herpes virus infections; including herpes simplex virus, cytomegalovirus and varicella zoster virus infections, and the highly pathogenic poxviruses (variola, vaccinia and monkey pox) and filoviruses (Ebola and Marburg).
AuthorsClaire Simons, Qinpei Wu, Thet Thet Htar
JournalCurrent topics in medicinal chemistry (Curr Top Med Chem) Vol. 5 Issue 13 Pg. 1191-203 ( 2005) ISSN: 1568-0266 [Print] United Arab Emirates
PMID16305526 (Publication Type: Journal Article, Review)
Chemical References
  • Antiviral Agents
  • Nucleosides
  • Nucleotides
Topics
  • Antiviral Agents (chemical synthesis, classification, therapeutic use)
  • Humans
  • Molecular Conformation
  • Nucleosides (chemical synthesis, classification, therapeutic use)
  • Nucleotides (chemical synthesis, classification, therapeutic use)
  • Virus Diseases (drug therapy, virology)
  • Viruses (drug effects)

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