Abstract |
Balsam of Peru (PB; Myroxylon pereirae) is a natural product derived from resin of a tropical tree (MyroxyIon balsamum (L.) Harms var. pereirae (Royle) Baillon). Because of its antiseptic and aromatic properties PB or PB-components can be found worldwide not only in many health care and cosmetic products, but also in food items and semiluxury food. PB contains a wide variety of potent contact allergens leading to hypersensitivity reactions not only after topical application but also oral uptake. We report a 51-year-old brewer with chronic eczema of the hands who showed delayed-type patch test reactions against PB and fragrance-mix. Oral PB-challenge led to exacerbation of the eczema 5 and in a repeated test 2 days later. We here review this probably quite often overlooked disease and the therapeutic consequences which require profound knowledge about the wide distribution of PB when advising the patient about a PB-restricted diet. In addition, this unusual case report demonstrates that one has to consider marked delayed hypersensitivity reaction when investigating a systemic contact allergy.
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Authors | Wolfgang Pfützner, Andrea Niedermeier, Peter Thomas, Bernhard Przybilla |
Journal | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
(J Dtsch Dermatol Ges)
Vol. 1
Issue 9
Pg. 719-21
(Sep 2003)
ISSN: 1610-0379 [Print] Germany |
Vernacular Title | Hämatogen-allergisches Kontaktekzem auf Perubalsam. |
PMID | 16285279
(Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Adrenal Cortex Hormones
- Balsams
- Food Additives
- Pharmaceutic Aids
- Peruvian balsam
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Topics |
- Administration, Topical
- Adrenal Cortex Hormones
(administration & dosage, therapeutic use)
- Balsams
(adverse effects)
- Dermatitis, Contact
(diagnosis, drug therapy, etiology)
- Food Additives
(adverse effects)
- Hand Dermatoses
(chemically induced, diagnosis, drug therapy)
- Humans
- Male
- Middle Aged
- Myroxylon
(adverse effects)
- PUVA Therapy
- Pharmaceutic Aids
(adverse effects)
- Skin Tests
- Smoking
(adverse effects)
- Time Factors
- Treatment Outcome
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