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[Systemic contact eczema against Balsam of Peru].

Abstract
Balsam of Peru (PB; Myroxylon pereirae) is a natural product derived from resin of a tropical tree (MyroxyIon balsamum (L.) Harms var. pereirae (Royle) Baillon). Because of its antiseptic and aromatic properties PB or PB-components can be found worldwide not only in many health care and cosmetic products, but also in food items and semiluxury food. PB contains a wide variety of potent contact allergens leading to hypersensitivity reactions not only after topical application but also oral uptake. We report a 51-year-old brewer with chronic eczema of the hands who showed delayed-type patch test reactions against PB and fragrance-mix. Oral PB-challenge led to exacerbation of the eczema 5 and in a repeated test 2 days later. We here review this probably quite often overlooked disease and the therapeutic consequences which require profound knowledge about the wide distribution of PB when advising the patient about a PB-restricted diet. In addition, this unusual case report demonstrates that one has to consider marked delayed hypersensitivity reaction when investigating a systemic contact allergy.
AuthorsWolfgang Pfützner, Andrea Niedermeier, Peter Thomas, Bernhard Przybilla
JournalJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (J Dtsch Dermatol Ges) Vol. 1 Issue 9 Pg. 719-21 (Sep 2003) ISSN: 1610-0379 [Print] Germany
Vernacular TitleHämatogen-allergisches Kontaktekzem auf Perubalsam.
PMID16285279 (Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)
Chemical References
  • Adrenal Cortex Hormones
  • Balsams
  • Food Additives
  • Pharmaceutic Aids
  • Peruvian balsam
Topics
  • Administration, Topical
  • Adrenal Cortex Hormones (administration & dosage, therapeutic use)
  • Balsams (adverse effects)
  • Dermatitis, Contact (diagnosis, drug therapy, etiology)
  • Food Additives (adverse effects)
  • Hand Dermatoses (chemically induced, diagnosis, drug therapy)
  • Humans
  • Male
  • Middle Aged
  • Myroxylon (adverse effects)
  • PUVA Therapy
  • Pharmaceutic Aids (adverse effects)
  • Skin Tests
  • Smoking (adverse effects)
  • Time Factors
  • Treatment Outcome

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