Primary duodenal diffuse large cell non-hodgkin lymphoma with involvement of ampulla of Vater: report of 3 cases.

Abstract

Primary gastrointestinal system lymphomas constitute about one third of all extranodal lymphomas. Duodenal involvement of the lymphoma is a rare condition. Periampullary lymphoma or lymphomatous involvement of ampulla of Vater is even rarer. Since, periampullary lymphoma is not easy to differentiate from epithelial carcinoma of these sites clinically and radiologically, accurate histopathological diagnosis is essential to plan optimal treatment strategy. Obstructive jaundice and the need for some form of drainage procedure and dose modification of the chemotherapy are additional challenges. In this report, we present three cases of duodenal diffuse large cell lymphoma with involvement of ampulla of Vater, two of whom presented with the initial signs of obstructive jaundice. One of the icteric patients was only diagnosed histopathologically following an explorative laparotomy with the initial diagnosis of carcinoma.

• Authors: Nuriye Yildirim, Berna Oksüzoğlu, Burçin Budakoğlu, Murat Vural, Hüseyin Abali, Doğan Uncu, Nurullah Zengin
• Journal: Hematology (Amsterdam, Netherlands) (Hematology) Vol. 10 Issue 5 Pg. 371-4 (Oct 2005) ISSN: 1024-5332 [Print] England
• PMID: 16273723 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Ampulla of Vater (diagnostic imaging, pathology)
• Common Bile Duct Neoplasms (diagnostic imaging, pathology)
• Duodenal Neoplasms (diagnostic imaging, pathology)
• Humans
• Jaundice, Obstructive (diagnostic imaging, pathology)
• Lymphoma, Large B-Cell, Diffuse (diagnostic imaging, pathology)
• Male
• Radiography