Comparison of the levels of heat resistance of wild-type, cpe knockout, and cpe plasmid-cured Clostridium perfringens type A strains.

Abstract

An enterotoxin (cpe) plasmid was cured from a Clostridium perfringens non-food-borne gastrointestinal disease (NFBGID) isolate, and the heat resistance levels of wild-type, cpe knockout, and cpe plasmid-cured strains were compared. Our results demonstrated that (i) wild-type cpe has no influence in mediating high-level heat resistance in C. perfringens and (ii) the cpe plasmid does not confer heat sensitivity on NFBGID isolates.

• Authors: Deepa Raju, Mahfuzur R Sarker
• Journal: Applied and environmental microbiology (Appl Environ Microbiol) Vol. 71 Issue 11 Pg. 7618-20 (Nov 2005) ISSN: 0099-2240 [Print] United States
• PMID: 16269817 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Bacterial Toxins
• Calcium-Binding Proteins
• Enterotoxins
• enterotoxin, Clostridium
• Type C Phospholipases
• alpha toxin, Clostridium perfringens

Topics

• Bacterial Toxins (genetics)
• Calcium-Binding Proteins (genetics)
• Clostridium perfringens (genetics, growth & development, physiology)
• Enterotoxins (genetics)
• Gene Deletion
• Gene Expression Regulation, Bacterial
• Heat-Shock Response
• Hot Temperature
• Plasmids (genetics)
• Spores, Bacterial (genetics, growth & development)
• Type C Phospholipases (genetics)