Parry-Romberg syndrome in association with anti-dsDNA antibodies: a case report.

Abstract

Parry-Romberg syndrome (PRS) is a rare and puzzling disorder that is characterized by progressive hemifacial atrophy. It involves mainly some or all tissues of one side of the face. A case of 21-year-old Caucasian man with hemifacial atrophy in the right facial region is reported. Serological studies with anti-single-stranded DNA (anti-ssDNA), anti-double-stranded DNA (anti-dsDNA), anticentromere (ACA) and antinuclear (ANA) antibodies were done. Anti-dsDNA antibodies was found positive, but the others were negative. Rheumatoid factor (RF) was also negative. Since PRS is rare and its association with anti-dsDNA antibodies was not reported before, this case appears to be the first report.

• Authors: M Gonul, B Dogan, Y Izci, G Varol
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 19 Issue 6 Pg. 740-2 (Nov 2005) ISSN: 0926-9959 [Print] England
• PMID: 16268883 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Antinuclear

Topics

• Adult
• Antibodies, Antinuclear (blood)
• Enzyme-Linked Immunosorbent Assay
• Facial Hemiatrophy (blood)
• Humans
• Male