Clinical efficacy of selamectin in the treatment of naturally acquired infection of sucking lice (Linognathus setosus) in dogs.

Abstract

A clinical study was performed in 21 dogs to evaluate the efficacy of selamectin for the treatment of naturally acquired infection of sucking lice (Linognathus setosus [L.setosus]) in dogs. Each dog was randomly assigned to one of two treatment groups. One group was treated with selamectin applied topically at a mean dosage of 7.9 mg/kg. The other group was treated with permethrin applied topically at a mean dosage of 85.7 mg/kg. At day 42 posttreatment, all animals remaining in the study (10 treated with selamectin and six with permethrin) were clear of lice. In both groups, the reduction in lice counts from pretreatment values to day 42 was statistically significant at P< or =0.0001. Selamectin applied topically appeared to be effective against L. setosus infection in dogs.

• Authors: Lotta Gunnarsson, Dan Christensson, Eleonor Palmér
• Journal: Journal of the American Animal Hospital Association (J Am Anim Hosp Assoc) 2005 Nov-Dec Vol. 41 Issue 6 Pg. 388-94 ISSN: 1547-3317 [Electronic] United States
• PMID: 16267063 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Antiparasitic Agents
• Ivermectin
• selamectin

Topics

• Administration, Topical
• Animals
• Antiparasitic Agents (therapeutic use)
• Dog Diseases (drug therapy)
• Dogs
• Dose-Response Relationship, Drug
• Female
• Ivermectin (analogs & derivatives, therapeutic use)
• Lice Infestations (drug therapy, veterinary)
• Male
• Phthiraptera
• Treatment Outcome