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Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis.

Abstract
In a phase 2 open-label, dose-ranging study in patients with candidemia, anidulafungin was effective in eradicating Candida albicans and other species of Candida. The anidulafungin MIC distribution showed that Candida albicans and C. glabrata were the most susceptible species and C. parapsilosis was the least susceptible species.
AuthorsM A Pfaller, D J Diekema, L Boyken, S A Messer, S Tendolkar, R J Hollis, B P Goldstein
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 49 Issue 11 Pg. 4795-7 (Nov 2005) ISSN: 0066-4804 [Print] United States
PMID16251335 (Publication Type: Clinical Trial, Phase II, Journal Article)
Chemical References
  • Antifungal Agents
  • Echinocandins
  • Peptides, Cyclic
  • Anidulafungin
Topics
  • Adult
  • Anidulafungin
  • Antifungal Agents (therapeutic use)
  • Candida (drug effects)
  • Candidiasis (drug therapy)
  • Echinocandins
  • Humans
  • Microbial Sensitivity Tests
  • Peptides, Cyclic (therapeutic use)

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