[Treatment of ulcerative colitis by combined therapy of retention enema and per-colonoscopic spraying with zhikang capsule compound liquid].

Abstract

OBJECTIVE:

To explore the therapeutic efficacy of patients with ulcerative colitis (UC) treated by retention enema and per-colonoscopic spraying of Zhikang Compound Liquid (ZKCL).

METHODS:

Eighty-six patients with UC were divided into two groups. The 52 patients in the treated group were treated for 4 courses of retention enema, the drug for enema used in the 1st course was ZKCL-A (consisted of normal saline, Zhikang capsule, gentamycin and dexamethasone) and smecta, in the 2nd course ZKCL-A alone, in the 3rd and 4th course, ZKCL-B (with the same contents of ZKCL-A but without dexamethasone), the enema was carried out once a day in the evening, 15 days as one course. Besides, local spraying of ZKCL-A and smecta were given once by colonoscopy before the 1st and 3rd course. The 34 patients in the control group were treated by salicylazosulfapyridine orally.

RESULTS:

In the treated group, 32 patients got complete remitted, 15 were treated effectively, 5 ineffectively, the total effective rate being 90.38% while the corresponding number in the control group were 8, 14, 12, and 64.71%, respectively. Significant difference was seen when compared with the therapeutic effects of the two groups. CONCLUSION Good efficacy was got in treating patients with UC by retention enema and per-colonoscopic spraying with ZKCL.

• Authors: Jie Zhang, Yu-feng Zeng, Bin-qiong Xiao, Juan Wang, Aihua Zhao
• Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 25 Issue 9 Pg. 839-42 (Sep 2005) ISSN: 1003-5370 [Print] China
• PMID: 16248252 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drugs, Chinese Herbal
• Gentamicins
• Dexamethasone

Topics

• Administration, Rectal
• Adult
• Aged
• Aged, 80 and over
• Colitis, Ulcerative (drug therapy, pathology)
• Colonoscopy
• Dexamethasone (administration & dosage)
• Drug Therapy, Combination
• Drugs, Chinese Herbal (administration & dosage)
• Female
• Gentamicins (administration & dosage)
• Humans
• Male
• Middle Aged
• Phytotherapy