Disappearance of honeycomb opacity of Thiel-Behnke corneal dystrophy after Thygeson superficial punctate keratitis.

Abstract

PURPOSE:

To present an unusual case in which the honeycomb opacities of Thiel-Behnke corneal dystrophy disappeared during a course of chronic Thygeson superficial punctate keratitis.

CASE:

A 29-year-old woman with a 5-year history of decreased visual acuity in both eyes had bilateral honeycomb-shaped corneal opacities, located mainly in the superficial central cornea. She was diagnosed as having Thiel-Behnke corneal dystrophy, which we confirmed genetically. During follow-up, her left eye was affected by chronic Thygeson superficial punctate keratitis, and the honeycomb opacity in this eye was noted to have disappeared.

CONCLUSIONS:

We observed the dissolution of honeycomb-like corneal opacities in a patient with confirmed Thiel-Behnke corneal dystrophy after the patient subsequently contracted chronic Thygeson superficial punctate keratitis. We surmise that epithelial inflammation associated with Thygeson epithelial keratitis may play a role in dissolving the honeycomb opacities.

• Authors: Akira Kobayashi, Shigeyuki Ijiri, Taeko Ohta, Kazuhisa Sugiyama
• Journal: Cornea (Cornea) Vol. 24 Issue 8 Pg. 1029-30 (Nov 2005) ISSN: 0277-3740 [Print] United States
• PMID: 16227859 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Glucocorticoids
• Ophthalmic Solutions
• Hyaluronic Acid
• Fluorometholone

Topics

• Adjuvants, Immunologic (administration & dosage, therapeutic use)
• Adult
• Cornea (pathology)
• Corneal Dystrophies, Hereditary (complications, pathology)
• Corneal Opacity (etiology, pathology)
• Drug Therapy, Combination
• Female
• Fluorometholone (administration & dosage, therapeutic use)
• Follow-Up Studies
• Glucocorticoids (administration & dosage, therapeutic use)
• Humans
• Hyaluronic Acid (administration & dosage, therapeutic use)
• Keratitis (complications, drug therapy, pathology)
• Ophthalmic Solutions
• Remission, Spontaneous