Abstract | OBJECTIVE: METHODS: RESULTS: In a multiple linear regression analysis, maximum gain in best-corrected visual acuity after the intravitreal injection of triamcinolone was significantly (P < .001) and negatively correlated with an increased degree of macular ischemia and a higher preoperative visual acuity. Improvement in best-corrected visual acuity was significantly and positively correlated with increased degree of macular edema (P = .001). Change in best-corrected visual acuity after the intravitreal triamcinolone injection was statistically independent (P > .15) of age, sex, pseudophakia, and macula grid laser treatment before inclusion into the study. The results were comparable for gain in visual acuity at 6 months after the injection. CONCLUSION: Pronounced macular edema may have a positive impact, and marked macular ischemia and a high preoperative best-corrected visual acuity may have a negative impact, on an increase in best-corrected visual acuity after intravitreal triamcinolone injection in patients with diabetic macular edema.
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Authors | Jost B Jonas, Peter Martus, Robert F Degenring, Ingrid Kreissig, Imren Akkoyun |
Journal | Archives of ophthalmology (Chicago, Ill. : 1960)
(Arch Ophthalmol)
Vol. 123
Issue 10
Pg. 1338-43
(Oct 2005)
ISSN: 0003-9950 [Print] United States |
PMID | 16219724
(Publication Type: Journal Article)
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Chemical References |
- Glucocorticoids
- Triamcinolone Acetonide
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Diabetic Retinopathy
(drug therapy, physiopathology)
- Female
- Follow-Up Studies
- Glucocorticoids
(therapeutic use)
- Humans
- Injections
- Macular Edema
(drug therapy, physiopathology)
- Male
- Middle Aged
- Prospective Studies
- Risk Factors
- Treatment Outcome
- Triamcinolone Acetonide
(therapeutic use)
- Visual Acuity
(physiology)
- Vitreous Body
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