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Results of silicone oil removal in patients with cytomegalovirus retinitis related retinal detachments.

AbstractPURPOSE:
To evaluate the percentage and risk indicators leading to retinal redetachment in HIV (human immunodeficiency virus) patients with CMV (cytomegalovirus) retinitis related retinal detachments that were repaired with silicone oil, and then subsequently underwent oil removal.
DESIGN:
Retrospective, noncomparative interventional case series.
METHODS:
The study cohort consisted of a series of 15 eyes in 14 patients with HIV and CMV retinitis with a retinal detachment (RD) repaired with silicone oil at a single center and followed from the time of the CMV retinitis diagnosis through the time of silicone oil removal. Patient- and eye-specific data regarding demographic and clinical characteristics were collected retrospectively and statistical analyses were performed to compare differences between the eyes that had retinal detachments versus the eyes that remained attached following removal of silicone oil.
RESULTS:
Eight eyes (53%) redetached after a median of 4.0 months following oil removal. Cataract surgery performed at the time of oil removal was a statistically significant risk factor for redetachment (P = .01). There was a trend for lower CD4 levels to be associated with a higher risk of retinal redetachment. The use of a scleral buckle at the time of surgery (initial RD repair or at the time of oil removal) did not reduce the risk of redetachment.
CONCLUSIONS:
Approximately half of the eyes with CMV related retinal detachment may safely undergo oil removal. The risk factor for redetachment was simultaneous cataract extraction at the time of silicone oil removal. There was also a trend for lower CD4 levels to be associated with a higher risk of retinal redetachment.
AuthorsVictoria L Morrison, Laurie D Labree, Stanley P Azen, Daniel E Goldberg, William R Freeman
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 140 Issue 5 Pg. 786-793 (Nov 2005) ISSN: 0002-9394 [Print] United States
PMID16214100 (Publication Type: Journal Article, Research Support, N.I.H., Extramural)
Chemical References
  • Silicone Oils
Topics
  • AIDS-Related Opportunistic Infections (complications, surgery)
  • Adult
  • CD4 Lymphocyte Count
  • Cytomegalovirus Retinitis (complications, surgery)
  • Drainage
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Retinal Detachment (etiology, surgery)
  • Retrospective Studies
  • Risk Factors
  • Scleral Buckling
  • Silicone Oils
  • Treatment Outcome
  • Vitrectomy

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