Abstract | PURPOSE OF REVIEW:
Coenzyme Q10 is administered for an ever-widening range of disorders, therefore it is timely to illustrate the latest findings with special emphasis on areas in which this therapeutic approach is completely new. These findings also give further insight into the biochemical mechanisms underlying clinical involvement of coenzyme Q10. RECENT FINDINGS: SUMMARY: The latest findings highlight the beneficial role of coenzyme Q10 as coadjuvant in the treatment of syndromes, characterized by impaired mitochondrial bioenergetics and increased oxidative stress, which have a high social impact. Besides their clinical significance, these data give further insight into the biochemical mechanisms of coenzyme Q10 activity.
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Authors | Gian Paolo Littarru, Luca Tiano |
Journal | Current opinion in clinical nutrition and metabolic care
(Curr Opin Clin Nutr Metab Care)
Vol. 8
Issue 6
Pg. 641-6
(Nov 2005)
ISSN: 1363-1950 [Print] England |
PMID | 16205466
(Publication Type: Journal Article, Review)
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Chemical References |
- Antioxidants
- Coenzymes
- Ubiquinone
- coenzyme Q10
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Topics |
- Antioxidants
(adverse effects, therapeutic use)
- Cardiovascular Diseases
(drug therapy)
- Coenzymes
- Friedreich Ataxia
(drug therapy)
- Humans
- Macular Degeneration
(drug therapy)
- Migraine Disorders
(drug therapy)
- Mitochondria
(metabolism)
- Oxidative Stress
(drug effects, physiology)
- Ubiquinone
(adverse effects, analogs & derivatives, therapeutic use)
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