Prevention of wound contamination using DuraPrep solution plus Ioban 2 drapes.

Abstract

The use of the preoperative skin preparation DuraPrep is thought to enhance the adhesion qualities of an incise drape. If there is less drape lift it was hypothesized that there may be a reduction in wound contamination. We did a single-center, randomized trial to determine if a preoperative skin preparation containing DuraPrep solution plus Ioban 2 drapes reduced wound contamination in total joint replacement surgery compared with a povidone iodine scrub and paint plus Ioban 2 drapes. Secondary research questions focused on comparisons of differences in drape lift and cost between the two groups. Of the 176 evaluable patients, the proportion of patients with a contaminated wound was similar in the two groups (DuraPrep 28.0% versus povidone iodine 36.4%). The mean drape lift in the DuraPrep group was less than the povidone iodine group (1.5 cm versus 9.9 cm respectively). The mean cost of prepping was lower for the DuraPrep group compared with the povidone iodine group (dollars 93.36 and dollars 248.91, respectively). A preoperative skin preparation regimen containing DuraPrep solution plus Ioban 2 drapes is equivalent to a povidone iodine scrub and paint and Ioban 2 for the prevention of wound contamination during total joint replacement surgery. Improved drape lift and cost may influence the choice between the two methods.

• Authors: Cassie Jacobson, Douglas R Osmon, Arlen Hanssen, Robert T Trousdale, Mark W Pagnano, Janine Pyrek, Elie Berbari, James Naessens
• Journal: Clinical orthopaedics and related research (Clin Orthop Relat Res) Vol. 439 Pg. 32-7 (Oct 2005) ISSN: 0009-921X [Print] United States
• PMID: 16205134 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Infective Agents, Local
• Povidone-Iodine

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Infective Agents, Local (administration & dosage, adverse effects)
• Arthroplasty, Replacement
• Cost Savings
• Disinfection (economics, methods)
• Female
• Hand Disinfection
• Humans
• Male
• Middle Aged
• Povidone-Iodine (administration & dosage, adverse effects)
• Preoperative Care (economics, methods)
• Prospective Studies
• Skin (microbiology)
• Surgical Equipment (economics)
• Surgical Wound Infection (economics, prevention & control)