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Dissolution of ureteral uric acid calculi with local litholytic irrigation.

Abstract
This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radiography (KUB), retrograde urography, ultrasonography (B-mode ultrasound), spiral computerized tomography(CT) and blood biochemical examinations. A ureteral catheter was passed retrogradely across ureteral calculi by cystoscopy. LLI with tromethamine-E (THAM-E) was performed via the ureteral catheter after the improvement of renal function and general situation and the control of urinary tract infection under the condition of intravenous application of antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones, 13 cases within 10 days and 1 within 12 days. Mild hematuria was observed in the majority of the cases and temporary aggravated lumbago in 1 case, with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral uric acid calculi for its advantages of shorter duration,lower cost, less physical suffering and no severe complications.
AuthorsZhiqiang Chen, Linfang Yao, Zhangqun Ye, Weimin Yang
JournalJournal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban (J Huazhong Univ Sci Technolog Med Sci) Vol. 25 Issue 3 Pg. 317-9 ( 2005) ISSN: 1672-0733 [Print] China
PMID16201283 (Publication Type: Journal Article)
Chemical References
  • Tromethamine
  • Uric Acid
  • Sodium Chloride
  • Potassium Chloride
Topics
  • Adult
  • Aged
  • Female
  • Humans
  • Middle Aged
  • Potassium Chloride (administration & dosage)
  • Sodium Chloride (administration & dosage)
  • Therapeutic Irrigation (methods)
  • Tromethamine (administration & dosage)
  • Ureteral Calculi (chemistry, therapy)
  • Uric Acid
  • Urinary Catheterization

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