Abstract | BACKGROUND/AIMS: METHODOLOGY: RESULTS: The peritoneal exudative neutrophil count was greater in edematous than in necrotizing pancreatitis. The number of CD11b-positive peritoneal exudative neutrophils was elevated in edematous pancreatitis, but the number was lower in necrotizing than in edematous pancreatitis at 6-24 hours. The mean fluorescence intensity of CD11b on neutrophils was comparable in both pancreatitis models. The cell count and mean fluorescence intensity indicated upregulated expression of CD32/CD16 on peritoneal exudative neutrophils in edematous pancreatitis, whereas the upregulation was attenuated in necrotizing pancreatitis. CONCLUSIONS:
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Authors | Masanori Sugiyama, Nobuhiko Hatano, Takashi Watanabe, Yutaka Atomi |
Journal | Hepato-gastroenterology
(Hepatogastroenterology)
2005 Sep-Oct
Vol. 52
Issue 65
Pg. 1591-5
ISSN: 0172-6390 [Print] Greece |
PMID | 16201123
(Publication Type: Journal Article)
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Chemical References |
- CD11b Antigen
- Receptors, IgG
- Receptors, Immunologic
- opsonin receptor
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Topics |
- Animals
- CD11b Antigen
(metabolism)
- Female
- Flow Cytometry
- Mice
- Mice, Inbred BALB C
- Neutrophils
(metabolism)
- Pancreatitis, Acute Necrotizing
(metabolism)
- Peritoneum
(cytology)
- Receptors, IgG
(metabolism)
- Receptors, Immunologic
(metabolism)
- Up-Regulation
(physiology)
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