Systemic lupus erythematosus due to Epstein-Barr virus or Epstein-Barr virus infection provocating acute exacerbation of systemic lupus erythematosus?

Abstract	Systemic lupus erythematosus (SLE) is a rheumatologic disease characterized by an inflammatory destruction of the target organ systems of the body in an unknown way by autoantibodies formed against self-antigens. Infectious agents like Epstein-Barr virus (EBV), cytomegalovirus and parvovirus B19 may have a role in the occurrence or the exacerbation of the SLE. In this report, the clinical follow-up of a 14-year-old girl diagnosed with SLE following an EBV infection with bicytopenia, lymphadenomegaly and hepatomegaly is discussed. This case could support the role of viral infections in the etiology of SLE.
Authors	Ozgur Kasapcopur, Yakup Ergul, Seyhan Kutlug, Cengiz Candan, Yildiz Camcioglu, Nil Arisoy
Journal	Rheumatology international (Rheumatol Int) Vol. 26 Issue 8 Pg. 765-7 (Jun 2006) ISSN: 0172-8172 [Print] Germany
PMID	16200398 (Publication Type: Case Reports, Journal Article)
Chemical References	Glucocorticoids Immunosuppressive Agents Cyclophosphamide
Topics	Adolescent Autoimmune Diseases (virology) Cyclophosphamide (therapeutic use) Drug Therapy, Combination Epstein-Barr Virus Infections (diagnosis) Female Follow-Up Studies Glucocorticoids (therapeutic use) Herpesvirus 4, Human (pathogenicity) Humans Immunosuppressive Agents (therapeutic use) Lupus Erythematosus, Systemic (etiology, pathology, therapy, virology) Time Factors Treatment Outcome

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