Comparison of Allevyn Adhesive and Biatain Adhesive in the management of pressure ulcers.

Abstract

OBJECTIVE:

The primary objective was to assess dressing delamination and the ensuing potential consequences during wear and/or removal, as well as the effect of residue remaining in the ulcer following foam breakdown.

METHOD:

In this prospective multicentre study, 32 patients with a grade II or III pressure ulcer were randomised to receive either Allevyn Adhesive or Biatain Adhesive dressing. The performance of the dressings was assessed over seven dressing changes or a maximum of six weeks. The primary efficacy variable was the proportion of patients with at least one delaminated dressing (delamination being defined as the falling apart of a dressing during wear or removal, or the presence of residue from the dressing in the ulcer).

RESULTS:

Allevyn Adhesive was significantly less likely to delaminate than Biatain Adhesive: 83% of patients given Biatain Adhesive had a dressing that delaminated compared with 14% for Allevyn Adhesive (p = 0.014). Furthermore, a greater proportion of the Biatain Adhesive dressings delaminated compared with the Allevyn Adhesive dressings: 50% versus 4% (p < 0.001). Allevyn Adhesive performed significantly better in the following parameters: handling exudate (p = 0.044), comfort (p = 0.007), ease of application (p = 0.004), conformability during application (p = 0.003) and removal (p < 0.0001), and adherence to the skin during application (p = 0.003) and prior to removal (p = 0.011). Three patients given Allevyn Adhesive (21%) reported three adverse events; six patients given Biatain Adhesive (33%) reported eight adverse events.

CONCLUSION:

Allevyn Adhesive is effective and well tolerated in the management of pressure ulcers and less likely to delaminate than Biatain Adhesive.

• Authors: P Amione, E Ricci, F Topo, L Izzo, R Pirovano, V Rega, C Cocci, M Masina
• Journal: Journal of wound care (J Wound Care) Vol. 14 Issue 8 Pg. 365-70 (Sep 2005) ISSN: 0969-0700 [Print] England
• PMID: 16178291 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Polyurethanes
• allevyn

Topics

• Adult
• Aged
• Aged, 80 and over
• Bandages, Hydrocolloid
• Equipment Failure
• Exudates and Transudates
• Female
• Humans
• Logistic Models
• Male
• Middle Aged
• Polyurethanes
• Pressure Ulcer (pathology, therapy)
• Prospective Studies
• Safety