[Efficacy of tracrolimus 0.1% ointment in prurigo].

Abstract

BACKGROUND:

Potent topical corticosteroids are used the intense pruritus in prurigo diseases. Their long-term application leads to local side effects such as atrophy and telangiectasia.

PATIENTS AND METHODS:

We treated 6 women (average age 64 years) with chronic prurigo with tacrolimus 0.1 % ointment (Protopic) to evaluate its efficacy in this clinical setting. Tacrolimus 0.1% ointment was applied twice a day for 4 weeks.

RESULTS:

After one week, both clinical improvement and reduced pruritus were observed in all patients.

CONCLUSION:

Tacrolimus 0.1% ointment represents a therapeutic option for the treatment of prurigo.

• Authors: Hae-Hyuk Lee, Wolfram Sterry, Margitta Worm
• Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (J Dtsch Dermatol Ges) Vol. 3 Issue 9 Pg. 690-4 (Sep 2005) ISSN: 1610-0379 [Print] Germany
• Vernacular Title: Wirksamkeit von Tacrolimus-0,1-%-Salbe bei Prurigoerkrankungen.
• PMID: 16173976 (Publication Type: English Abstract, Journal Article)

Chemical References

• Immunosuppressive Agents
• Ointments
• Tacrolimus

Topics

• Aged
• Aged, 80 and over
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Humans
• Immunosuppressive Agents (administration & dosage, adverse effects)
• Middle Aged
• Ointments
• Prurigo (drug therapy)
• Tacrolimus (administration & dosage, adverse effects)
• Treatment Outcome