Abstract |
Negative ions are considered to have potential health benefits, but few studies have examined their effects in vivo. We studied water-generated negative ions (WNI) with respect to physical properties as well as immunologic activation and anti- tumor activity (inhibition of carcinogenesis and tumor growth) in mice. Electrically, generated negative ions (ENI) served as control. Water-generated negative ions had a long life, significantly enhanced the cytotoxic activity of natural killer cells, and significantly decreased the incidence of cancer and inhibited tumor growth. Anti- tumor effects were attributed to enhancement of natural killer cell activity. The mechanisms and applications of negative ions warrant further investigation.
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Authors | Roppei Yamada, Syunsuke Yanoma, Makoto Akaike, Akira Tsuburaya, Yukio Sugimasa, Shoji Takemiya, Hisahiko Motohashi, Yasushi Rino, Yoshinori Takanashi, Toshio Imada |
Journal | Cancer letters
(Cancer Lett)
Vol. 239
Issue 2
Pg. 190-7
(Aug 08 2006)
ISSN: 0304-3835 [Print] Ireland |
PMID | 16171944
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Anions
- Cell Transformation, Neoplastic
(immunology)
- Killer Cells, Natural
(immunology)
- Mice
- Water
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